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Presentation
"Dr. Gavin Concludes"
Dr. James R. Gavin (biography) English - 2004-06-04 - 8 minutes
(2 slides)
Summary : Diabetes is now understood to be a complex metabolic disease involving the accelerated development of vascular abnormalities and atherosclerosis.
The treatment strategy would now maintain aggressive lifestyle interventions for promoting insulin sensitivity, and focus on earlier use of combination therapy in lieu of uptitration in monotherapy. It is now thought that early intervention with a TZD may preserve beta cell function. Metformin was shown in the UKPDS to improve vascular outcomes, and outcome studies are underway to determine the cardiovascular benefits of TZDs.
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